Prodotto
Cibides lipogel® ad azione lenitiva contiene:
- Olio di canapa*
- Escina
- Estratto di Boswellia
- Skinasensil
- Bromelina
- Metilsulfonilmetano
- Glucosammina solfato
- Metilsalicilato
Tra i diversi attivi contiene Il cannabidiolo, noto anche come 2-[(1R,6R)-3-metil-6-(prop-1-en-2-il)cicloes-2-enil]-5-pentilbenzen-1,3-diolo o con l’acronimo CBD, che è un metabolita 15 farmacologicamente attivo della Cannabis sativa con azioni documentate nel trattamento del dolore articolare.
La presenza di altri attivi tra cui escina, boswella ed MSM anch'essi di documentata efficacia ottimizzano gli effetti della preparazione in una forma farmaceutica innovativa, il lipogel.
Ingredienti
Aqua, alcohol denat., glycerin, escin, bromelain, dimethyl sulfone, glucosamine sulfate, cannabis sativa seed oil°, methyl salicylate, acetyl tetrapeptide-15, coco-glucoside, boswellia serrata gum extract, dicaprylyl ether, sodium hydroxide, carbomer, phenoxyethanol, caprylyl glycol, decylene glycol, sodium dehydroacetate.
Modalità d’uso
Applicare al mattino ed alla sera sulla zona interessata. Massaggiare delicatamente dal basso verso l’alto fino a completo assorbimento.
Evidenze scientifiche sui principi attivi
- Serpell M, et al. A double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatment. Eur J Pain. 2014 Aug;18(7):999-1012.
- Blake DR, et al. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford). 2006 Jan;45(1):50-2.
- Wetzel D, et al. Escin/diethylammonium salicylate/heparin combination gels for the topical treatment of acute impact injuries: a randomised, double blind, placebo controlled, multicentre study. Br J Sports Med 2002;36:183-188.
- Belcaro G, et al. Management of osteoarthritis (OA) with the pharma-standard supplement FlexiQule (Boswellia): a 12-week registry. Minerva Gastroenterol Dietol. 2015 Oct 2.
- Brien S, et al. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies. Evid Based Complement Alternat Med. 2004 Dec; 1(3): 251-257.
- Kim LS, et al.Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006 Mar;14(3):286-94.
- Debbi EM, et al. Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complement Altern Med. 2011 Jun 27;11:50.
- Drovanti A, et Al. Therapeutic activity of oral glucosamine sulfate in osteoarthrosis: a placebo-controlled, double blind investigation. Clinical Therapeutics, 1980; 3 ( 4 ): 260-272.
- Usha P.R., Naidu MUR. Randomised, Double-Blind, Parallel, Placebo-Controlled Study of Oral Glucosamine, Methylsulfoylmethane and their Combination in Osteoarthritis. Clinical Drug Investigation 24 ( 6 ): 353-363, 2004.
- Higashi Y, et al. Efficacy and Safety Profile of a Topical Methyl Salicylate and Menthol Patch in Adult Patients With Mild to Moderate Muscle Strain: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multicenter Study. Clin Ther. 2010 Jan;32(1):34-43.